What the screen does
StackShield separates the submitted list at commas, semicolons, and line breaks, then compares those entries with 43 curated interaction rules. Matching uses a finite list of generic names, selected brand names, classes, supplements, foods, and condition terms. Results show matched item pairs and a local educational severity label.
Direct primary-source links are currently attached to 18 priority rules. Sources include current submitted prescribing information on DailyMed and an FDA drug-safety communication. The other 25 rules do not yet carry rule-level provenance and should be checked against current sources before reliance.
Coverage is limited
- This is not a complete interaction database and it is not continuously synchronized with drug-label changes.
- Names, spellings, brands, ingredients, or combinations absent from the local aliases and rules can be missed.
- The screen does not evaluate dose, timing, route, allergies, diagnoses, pregnancy, lab results, kidney function, genetics, or the complete product label.
- A clear result does not confirm that a combination is safe.
Do not start, stop, replace, or change a medicine or supplement because of this screen. Review the complete list and current labels with a pharmacist or prescriber.
Authoritative resources for human review
- FDA — Drug Interactions: What You Should Know
- NLM DailyMed — current submitted product labeling and its limits
- NIH Office of Dietary Supplements — fact sheets and medicine-interaction resources
Labels and evidence change. Use current product labeling and a pharmacist or prescriber for decisions about a specific person.